hrp0094p2-387 | Pituitary, neuroendocrinology and puberty | ESPE2021

Isolated central diabetes insipidus and periventricular nodular heterotopia in a 9-year-old girl

Haufler Florentina , Walleczek Nina-Katharina , Vodopiutz Julia , Haeusler Gabriele , Raimann Adalbert ,

Background: Periventricular nodular heterotopia (PNH) is a brain malformation caused by dysregulation of neuronal migration during cerebral development, resulting in nodular neuronal structures in the ventricular surface. Associated ectopy of the posterior pituitary has been reported in literature and is usually associated with deficiencies of the anterior pituitary. The occasion of an isolated central diabetes insipidus due to absence of the posterior pituita...